Biden tests negative again, will quarantine until confirmed

President Joe Biden tested negative for COVID-19 on Saturday after a “bounce” of virus cases, but will remain in isolation until he gets another negative test, his doctor said.

Dr Kevin O’Connor writes in daily update that “strict quarantine measures” will continue “with great caution” White House release.

Biden initially tested positive on July 21 after a week-long trip to the Middle East, but he tested negative for the virus when he ended his quarantine on July 26-27.

He also tested negative on July 28 and July 29, and then tested positive again on July 30, according to a letter from O’Connor to White House press secretary Karin Jean-Pierre.

“Bounce COVID”, Paxlovid and more

Biden reportedly received COVID-19 antiviral drug Paxlovid on day of diagnosis multiple news media. This is a pill approved to treat COVID-19 in high-risk adults, such as older adults, and has received emergency use authorization from the U.S. Food and Drug Administration.

But the drug is known for “bounce back” cases, which the US Centers for Disease Control and Prevention refers to as a “brief recovery of symptoms.”

However, this rebound could happen with or without Paxlovid, Andy Pekosz, a virologist at the Johns Hopkins Bloomberg School of Public Health, told recently. wealth.

“It’s not uncommon for people to test positive days after testing negative for COVID-19,” he said. “I think people are now more focused on whether this could be a rebound for Paxlovid, which means he gets the virus again.”

While the CDC says COVID rebounds are rare, they may be more common than we know because most COVID patients stop testing after receiving negative results.

“The White House is testing people every day, and it’s doing a really good job,” Pekosz said. “They’re more likely to catch these rare things with that frequency.”

O’Connor wrote that the president’s rebound-positive test was an antigen or rapid test. Antigen tests have an advantage in gauging whether someone is shedding live virus and therefore contagious, Pekosz said, adding that a positive antigen test “could be a good reason to re-isolate.”

Fauci’s Paxlovid bounces back

When diagnosed with coronavirus in June, chief presidential medical adviser Dr. Anthony Fauci Prescribes Antiviral Drugs Because of his advanced age, this puts him at greater risk of severe COVID-19 consequences, even though he has been fully vaccinated and boosted twice.

Fauci later said he experienced a Paxlovid rebound.

“After I finished my five-day Paxlovid, I came back with a negative antigen test three days in a row,” Fauci, 81, said in a statement. foreign policy’Global Health ForumBloomberg report. “Then on the fourth day, to be absolutely sure, I tested myself again.”

“I got my positive attitude back.”

Fauci later told New York Times Paxlovid kept him out of the hospital and stopped his infection from getting worse in the first place, saying: “Paxlovid did what it was supposed to do.”

Fauci started a second course of Paxlovid when symptoms appeared “much worse than the first go-around,” he said. In May, the CDC issued a health advisory on such rebounds, saying there was no evidence that the rebounding cases required additional treatment.

in June, PfizerThe company that makes Paxlovid has announced that it will stop adding new participants to a trial of the drug in COVID patients with a low risk of hospitalization and death. According to Bloomberg, the study failed to show that the drug reduced symptoms, hospitalizations and deaths in a statistically significant way.

However, Pekosz warns that Paxlovid probably doesn’t deserve a bad name.

“I would still point to the fact that it plays a role in keeping people out of hospitals — that’s the most important thing right now,” he said, adding that it may need to be re-tuned to better address the Omicron sub-variant.

How long are you in quarantine?

The CDC currently recommends that COVID-positive people isolate for five days (and wear them in public for another five days) before returning to normal life. The recommended quarantine period is 10 days, until the federal health agency halved it in December.

But “there is no data to support 5 days or anything shorter than 10 days,” said Amy Barczak, a physician in the department of infectious diseases at Massachusetts General Hospital. recently told nature.

some scientists have reason for questioning Since the CDC introduced the policy late last year.Now critic There’s more data to back up their claims: Even healthy vaccinated adults can shed virus for more than 10 days, according to a London preprint Posted this month.

Some scientists are advising people to stop quarantining only after using a negative home test, rather than relying solely on the CDC’s five-day rule.

Biden did, however, testing negative five and six days after infection and then ending his quarantine.White House has Say Biden will “go beyond” the CDC’s five-day guidance to wait until he tests negative before returning to public life.

He clearly didn’t expect a rebound.

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